How Alcohol Affects Your Liver Enzymes and Triglycerides: What Your Blood Test Reveals

Published: June 2025

Drinking raises ALT, GGT, AST and triglycerides — early signs of liver stress. Learn how alcohol affects your biomarkers and how to reverse the damage.

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Your after-work drink may seem harmless, but even moderate alcohol intake can affect your liver and metabolic blood markers. The liver metabolises alcohol, and chronic or heavy drinking can elevate enzymes like ALT (GPT), AST (GOT), and Gamma-GT (GGT) — often the first signs of liver inflammation or fatty liver disease [ScienceDirect].

Frequent alcohol consumption can also increase ferritin, a marker of stored iron, as inflamed liver cells release ferritin into circulation. On top of this, alcohol’s high sugar content can spike triglycerides, especially when consumed alongside poor diet or inactivity [PubMed].

While a small glass of red wine may modestly boost HDL cholesterol, excessive or daily drinking generally does more harm than good — affecting both liver function and cardiovascular risk markers.

💡 Practical Takeaways:

Test for these Biomarkers:

ALT, AST, GGT, Triglycerides, Ferritin, HDL Cholesterol