Inflammaging: Why Inflammation Rises with Age and What You Can Do About It

As we age, our bodies undergo a subtle but chronic shift in immune function, leading to what's known as inflammaging – a persistent, low-grade elevation in inflammatory markers like CRP, IL-6, IL-1, and TNF-α [Longevity & Healthspan].

This shift isn't due to a single disease or infection. It stems from factors like immune senescence, oxidative stress, past infections, and accumulation of cellular debris. Unfortunately, this background inflammation is linked to nearly every age-related disease: from cardiovascular issues to frailty, Alzheimer's, and cancer.

Yet, not all seniors have the same levels of inflammatory markers. Diet, exercise, body composition, and gut health influence inflammaging. Regular physical activity, anti-inflammatory diets (e.g., Mediterranean), and maintaining healthy weight are all linked to lower CRP and IL-6 in older adults.

💡 Practical Takeaways:

• CRP & Cytokines Rise with Age: Inflammation increases even without acute illness.
• Linked to Frailty and Disease: Especially neurodegeneration and vascular decline.
• Modifiable Through Lifestyle: Diet, movement, and gut health all help control inflammaging.

Test for these Biomarkers:

CRP, IL-6, TNF-α, IL-1, Albumin, Oxidative Stress Markers

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