If you are looking for the most comprehensive private blood test available in Britain, this is the short answer: the TrueVitals Signature panel, 230 biomarkers, processed by Randox Health, £799 with clinic phlebotomy included. Randox's own equivalent programme costs around £2,112. No other mainstream UK provider tests beyond 100 markers in a single panel. Below is the full comparison, and an honest account of when you do not need this much.
Randox Health is one of the largest clinical diagnostics companies in the world, developing more diagnostic tests than any other firm globally, with equipment used in laboratories across 145 countries. Their own flagship Signature Prestige programme is the benchmark for depth in the UK private market.
The TrueVitals Signature panel is processed by those same Randox laboratories at comparable biomarker depth. The difference in price is not a difference in the blood work. It is that Randox Prestige bundles in-clinic consultations and a follow-up appointment programme, where TrueVitals delivers the data with an AI-powered personalised report and medical professional review.
If you want the clinical relationship and face-to-face consultations, Randox Prestige delivers that and it is a legitimate product. If you want the depth and an intelligent report, you are paying £1,313 less for the same laboratory work. Full Randox comparison.
Every major UK private blood testing service, ranked by the biomarker count of its deepest single panel. Prices verified August 2026 and shown all-in where collection is charged separately.
| Provider | Max Biomarkers | Hormones | Full Thyroid | ApoB / Lp(a) | Insulin / HOMA | Tumour Markers | Collection | Report | All-in Price |
|---|---|---|---|---|---|---|---|---|---|
| TrueVitals Signature | 230 | Full panel | TSH + FT3 + FT4 + Ab | Both, extended | Full metabolic | Extended | Venous, Randox clinic, included | AI report + medical review | £799 |
| Randox Signature Prestige | ~230 | Full panel | Yes | Both | Yes | Yes | Venous, Randox clinic | Dashboard + consultation | ~£2,112 |
| TrueVitals Ultimate | 114 | Full panel | TSH + FT3 + FT4 + Ab | Both | Insulin + HOMA-IR | 7 markers | Venous, clinic or home | AI report + medical review | £368 |
| Randox Everyman/woman | ~100 | Yes | Yes | ApoB only | Insulin only | Yes | Venous, Randox clinic | Dashboard | £416 |
| Lola Health Peak | ~70 | Yes | TSH + FT4 only | No | No | No | Venous, major cities | Basic report | ~£285 |
| Medichecks Optimal | ~59 | Partial | TSH + FT4 only | No | No | No | Finger-prick, venous extra | Dashboard | £274-308 |
| Forth Vitality | ~50 | Partial | TSH + FT4 | No | No | No | Finger-prick, venous extra | HealthCoach scoring | ~£244 |
| Thriva | ~40-50 | Partial | TSH only | No | No | No | Tasso+ shoulder device | App dashboard | ~£99-149 |
| Bupa Comprehensive | ~30-40 blood | Partial | Limited | No | No | Some | Venous, Bupa centre | Clinician consultation | £1,199 |
| NHS (GP request) | 10-20 | Only if indicated | TSH first, others rarely | No | No | No | Venous at GP or hospital | Phone call or letter | Free |
Biomarker counts are approximate where providers bundle or vary by configuration. All-in price includes venous collection where charged separately. Bupa and Randox Prestige include clinician consultation and physical assessments, which the blood-only count does not reflect. Full provider comparison. Cost per biomarker breakdown.
The Ultimate panel at 114 biomarkers already covers every major system: full hormones, complete thyroid with antibodies, ApoB and Lp(a), fasting insulin and HOMA-IR, cystatin C, tumour markers, immunoglobulins and coeliac screening. It is a genuinely comprehensive test and it is what most people should buy.
Signature adds another 116 markers on top. Here is honestly what that buys, and who it is for.
Markers relevant to cognitive and nerve function that sit outside a standard comprehensive panel. Relevant if you have unexplained cognitive symptoms or a family history worth monitoring.
H. pylori, pepsinogen and gastrin. These assess stomach lining health and infection status directly, rather than inferring gut issues from inflammation markers alone.
Beyond rheumatoid factor and thyroid antibodies into a wider antibody panel. Useful where symptoms suggest autoimmune activity but a standard screen has come back unremarkable.
A broader screening set than the seven in Ultimate. Not diagnostic on their own, and never a substitute for national screening programmes, but part of a thorough baseline.
EBV antibody status is genuinely useful in long-running unexplained fatigue, where reactivation is a question a standard panel cannot answer.
Blood pressure, height, weight, waist and hip circumference, resting pulse. Taken at your appointment and integrated into the report, so metabolic risk is assessed against real body composition rather than blood alone.
This page exists to answer a specific question, and the honest answer to "what is the most comprehensive blood test in the UK" is the 230-marker Signature panel. But "most comprehensive" and "right for you" are different questions, and it would be poor advice to conflate them.
The Ultimate panel at £349 is the right choice for most people. It covers every clinically actionable system. If you want to know why you are tired, whether your hormones are where they should be, whether you are heading toward insulin resistance, or what your real cardiovascular risk is, 114 biomarkers answers all of that. The extra 116 in Signature are depth for specific situations, not a better answer to ordinary questions.
Signature earns its price in four situations. Executive health screening where the point is maximum coverage in one sitting. Complex or long-running symptoms where standard comprehensive testing has already come back unremarkable. A family history that makes broader screening genuinely worthwhile. Or simply wanting the deepest picture available and being comfortable paying for it.
And the NHS is still the right answer sometimes. Acute symptoms, anything needing clinical assessment rather than data, and monitoring of a diagnosed condition all belong with your GP. NHS versus private comparison.
Every panel includes AI-powered cross-system reporting and medical professional review before release.
74 BIOMARKERS · £269
Full blood count, liver, kidney, electrolytes, cholesterol with ApoB, iron studies, vitamins, thyroid with Free T3, core hormones, hs-CRP, cardiac markers, bone minerals and urinalysis. A comprehensive baseline. Report in 4 working days.
114 BIOMARKERS · £349 · MOST CHOSEN
Everything in Advanced plus complete hormones, seven tumour markers, immunoglobulins and autoimmune screening, coeliac markers, fasting insulin with HOMA-IR, cystatin C, Lp(a) and parathyroid hormone. Report in 4 working days.
230 BIOMARKERS · £799 · DEEPEST IN THE UK
Everything in Ultimate plus neurological markers, digestive and gastric health, extended autoimmune and tumour profiling, Epstein-Barr antibodies and physical measurements. Randox Health laboratories, clinic phlebotomy included. Report in 12 working days.
The TrueVitals Signature panel at 230 biomarkers, processed by Randox Health for £799 with clinic phlebotomy included. Below that, the TrueVitals Ultimate panel tests 114 biomarkers for £349. Randox's own Signature Prestige programme tests comparable depth at approximately £2,112. No other mainstream UK provider exceeds 100 biomarkers in a single panel.
At least 70 across hormones, thyroid, cardiovascular, liver, kidney, inflammation, vitamins, minerals and metabolic markers. Below that you are missing entire systems. The deepest panels reach 200 or more and add neurological, extended autoimmune, digestive and viral markers.
For most people, no. The 114-marker Ultimate panel covers everything clinically actionable and is what most customers choose. Signature is worth it for executive screening, complex or unresolved symptoms, relevant family history, or simply wanting maximum coverage. It is depth for specific situations rather than a better answer to ordinary questions.
Same Randox laboratories, comparable depth. Randox Signature Prestige at roughly £2,112 includes in-clinic consultations and a follow-up appointment programme. TrueVitals Signature at £799 delivers the same laboratory work with an AI-powered report and medical professional review, without the consultation programme. Full comparison.
Deeper panels take longer because more assays are run. Signature at 230 biomarkers is delivered within 12 working days of your appointment. Advanced and Ultimate are delivered within 4 working days of your blood draw.
NHS blood tests are limited to what is clinically indicated at that moment, typically 10 to 20 markers. GPs cannot order comprehensive hormone panels, advanced lipids or tumour marker screening as routine care, and some labs reject markers like Free T3 outside local protocol. What to ask your GP for.
The deepest private blood test available in the UK, with clinic phlebotomy included and an AI-powered report reviewed by a medical professional.
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