Biomarker guide · Metabolic health

C-peptide blood test in the UK

A C-peptide blood test shows how much insulin your pancreas is actually making. In the UK you can get it privately in TrueVitals Ultimate (£399 including the clinic draw, 140 biomarkers), where it sits alongside fasting insulin, glucose, HbA1c and the HOMA-IR insulin resistance score. It is not in our Advanced panel.

In: Ultimate & SignatureFrom: £399 incl. drawSample: Fasted venous bloodResults: 4 working days (Ultimate)

What C-peptide is

When your pancreas makes insulin, it cuts one long molecule (proinsulin) into two pieces: insulin and C-peptide. They leave the pancreas in equal amounts. Insulin is cleared quickly by the liver, but C-peptide stays in the blood longer and more steadily, so it is a cleaner read on how hard your pancreas is working.

That makes it useful in two situations: telling apart the main types of diabetes, and spotting a pancreas that is pumping out extra insulin to keep blood sugar normal, which is the hidden stage of insulin resistance.

Who it is useful for

  • Anyone checking for insulin resistance. High fasting C-peptide with normal glucose suggests your body is compensating, often years before HbA1c moves. See our insulin resistance test guide.
  • People with prediabetes or type 2 diabetes who want to know how much insulin they still make. See prediabetes blood test.
  • People on GLP-1 medicines (Mounjaro, Wegovy) tracking metabolic change over time.
  • Anyone already on insulin injections. Injected insulin does not contain C-peptide, so C-peptide shows your own production separately.

What high and low results can mean

Higher than range

  • Insulin resistance (the pancreas is overproducing)
  • Early type 2 diabetes
  • Reduced kidney function (C-peptide is cleared by the kidneys)
  • Not fasting before the test
  • Rarely, an insulin-producing tumour (insulinoma)

Lower than range

  • Type 1 diabetes or LADA (the pancreas makes little insulin)
  • Long-standing type 2 diabetes with beta-cell decline
  • Low blood sugar from injected insulin
  • Damage to the pancreas

One result never diagnoses diabetes. A GP diagnoses it from HbA1c or glucose; C-peptide helps explain the picture.

Typical ranges

Fasting C-peptide is commonly reported in the region of 0.3 to 1.3 nmol/L (about 300 to 1,300 pmol/L), but ranges and units differ between labs. Your TrueVitals report always uses the lab's own range for your sample and explains where you sit within it.

Where to get a C-peptide test in the UK

OptionIncludes itPriceWhat else you get
TrueVitals UltimateYes£399 incl. clinic draw (home visit £29 extra)With fasting insulin, glucose, HbA1c, HOMA-IR and HOMA-B. Clinician-reviewed report in 4 working days.
TrueVitals SignatureYes£799 incl. draw230 biomarkers at Randox Health clinics, up to 12 working days.
TrueVitals AdvancedNo£319Not included. Advanced has glucose and HbA1c but not insulin or C-peptide.
NHS GPOn requestFree if clinically indicatedUsually only requested to classify diabetes, not for insulin resistance checks.

TrueVitals prices checked 5 November 2026. Every TrueVitals report is clinician-reviewed. Pay in instalments with Klarna or Clearpay. Book a draw at one of 103 partner clinics, or add a home visit.

Be honest with yourself about what this test is for

When you should not use a private test: if you have symptoms of high blood sugar (heavy thirst, passing a lot of urine, weight loss you can't explain, blurred vision), see your GP or call 111 the same day. That needs urgent glucose testing, not a booked panel.

A private panel is a good way to get a baseline, understand a result in context and track it over time. It does not replace your GP for symptoms, and anything that needs follow-up is flagged in plain words in your report.

Read alongside

C-peptide on its own rarely tells the whole story. In TrueVitals panels it is reported with these related markers:

Frequently asked questions

Do I need to fast for a C-peptide test?

Yes. Fast for 8 to 12 hours beforehand (water is fine) and book a morning appointment. Eating raises C-peptide, so a non-fasted result is hard to read. Our fasting guide covers the details.

Is C-peptide better than an insulin test?

They answer slightly different questions, which is why Ultimate measures both. C-peptide is steadier and is not affected by insulin injections; fasting insulin is used for the HOMA-IR score. Read together with glucose they give a fuller picture than either alone.

How much does a C-peptide blood test cost in the UK?

In TrueVitals Ultimate it comes as part of 140 biomarkers for £399 including the clinic blood draw. Some clinics sell it on its own, but you would still need glucose and insulin alongside it to interpret it properly.

Can C-peptide tell if I have type 1 or type 2 diabetes?

It helps. Low C-peptide points towards little insulin production, as in type 1 or LADA; normal or high points towards type 2. A diagnosis of type should be made by your GP or diabetes team, often with antibody tests too.

Is C-peptide in the Advanced panel?

No. C-peptide, fasting insulin and the HOMA scores are in Ultimate and Signature only. Use our panel comparison to check any marker.

Does kidney function affect C-peptide?

Yes. C-peptide is cleared by the kidneys, so reduced kidney function can push it up. Ultimate includes creatinine, eGFR and cystatin C, so your report reads C-peptide in that context.

Related guides

How this page was written: by James Smillie, founder of TrueVitals, reviewed by the TrueVitals clinical review team, using NHS and laboratory reference sources. Ranges are typical values; your report uses your lab's own ranges. TrueVitals sells the panels named on this page, so we have stated plainly what this test cannot do. Last updated 5 November 2026.

Test it properly, with the context around it

Ultimate: 140 biomarkers (139 for women), £399 including the clinic draw, home visit £29 extra. Clinician-reviewed report within 4 working days.

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