TrueVitals was founded by James Smillie after his own health problem went unexplained for years. A comprehensive blood test found what repeated GP appointments had missed. He built the company so that other people would not have to get lucky to find their answer.
James had a health problem he found embarrassing, and like most people in that position he put off doing anything about it for a long time. When he did eventually see his GP, he came away without an answer. He went back several times over an extended period, and each visit ended the same way. No cause identified, nothing showing on the tests that were run, no clear explanation for what he was experiencing.
Eventually the conversation moved, gently and with good intentions, towards the possibility that the problem was psychological rather than physical. Stress, perhaps. Anxiety. Something that would settle on its own.
This is not a criticism of the GPs involved. General practice is built to identify and treat what is clinically indicated for the symptom presented, within a ten minute appointment and a finite budget, and for acute illness it does that job very well. But it means a thorough NHS panel typically covers ten to fifteen markers. If the answer sits outside those fifteen, it does not get found.
Having run out of other options, James paid for a comprehensive private blood test. One hormone came back at more than twice the upper limit of its reference range. That single result went a long way towards explaining what he had been living with, and more importantly it gave him something that could actually be treated. The problem was resolved.
What stayed with James afterwards was not relief. It was how close he had come to never finding out at all. He found the answer because he could afford to look for it privately, and because he happened to keep pushing when it would have been easier to accept the explanation he had been given.
A great many people do neither. They accept that nothing is wrong, assume it is stress, and carry something for years that a single blood draw would have identified in an afternoon.
Comprehensive blood testing is not exotic technology. The assays exist and the laboratories exist. The barriers have historically been cost and comprehension. Most private tests are expensive, and most of them return a PDF of numbers with red and green arrows, which tells the average person very little unless they already know how to interpret it.
The objective became straightforward. Test broadly enough that important things are not missed. Price it so that ordinary people can reach it. And explain the results properly, in language someone can actually act on.
TrueVitals was not built alone, and it would have been considerably worse if it had been.
Curated alongside doctors, dieticians and biomedical scientists. Built as a deliberate spread across every major body system, including markers the NHS rarely orders and that most private providers leave out entirely.
Developed with Robert Smillie, James's brother, who works in artificial intelligence and data science at a hedge fund in San Francisco. The framework reads every biomarker against every other, and against the customer's lifestyle answers.
Partnerships with UKAS-accredited UK laboratories and a phlebotomy network covering 103 clinics plus at-home visits across more than 200 areas. Professional venous collection everywhere, never a finger-prick kit.
The reporting framework is the part that makes the difference. A single marker in isolation often means very little. The same ferritin reading means something quite different depending on inflammation markers, iron studies, training load and recent illness. Reading results as a connected system rather than a list of separate numbers is what turns data into something a person can use, and it is the thing almost nobody else in the market does.
Every report is reviewed by a medical professional before it is released. That step is not automated and will not be.
TrueVitals is a small company working with a much larger group of people, and the service depends on all of them. The phlebotomists who take the sample, often in someone's kitchen at eight in the morning. The laboratory technicians who process it. The customer service team who answer the questions that come in at all hours. The report team who make sure that what lands in a customer's account is accurate, clear and worth reading.
Across TrueVitals and its partners, everyone involved believes in what the company is trying to do, and that is largely because they have seen the effect it has already had. People have found explanations for symptoms they had carried for years. Others have caught something early enough to do something about it. Plenty have simply had the reassurance of knowing where they stand.
That is the point of the whole exercise, and it is why the standard does not slip.
James remains closely involved in the day to day running of the business rather than sitting above it. He handles a large share of customer enquiries himself, from panel questions before purchase through to helping people understand what their results actually mean afterwards.
Anyone who orders a panel has a reasonable chance of dealing with him directly as their account manager, rather than working through a support queue. For a company selling something as personal as this, that is deliberate.
"It's deeply rewarding seeing the epiphanies or relief our customers experience first hand. I'll always stay very close to the operation of this business for that reason alone."
TrueVitals is not a replacement for a GP, and is not intended to be. Anyone with acute symptoms, chest pain, unexplained weight loss, a lump, or anything requiring clinical assessment rather than data should see a doctor. Anyone being monitored for a diagnosed condition already has that care through the NHS, free of charge.
What TrueVitals provides is different. It is a broad, proactive picture of how the body is functioning at a point when someone is not ill enough to trigger investigation, but knows that something is not right. That is the gap James fell into, and it is the gap the NHS was never designed to cover.
No blood panel detects everything, and a normal result does not exclude illness. TrueVitals says so plainly, and flags clearly when a result warrants a conversation with a clinician.
The ambition is not complicated. Comprehensive blood testing should become a normal thing that people do periodically, in the way an annual dental check is normal, rather than something reserved for the wealthy or the desperate.
In practice that means holding prices where ordinary people can reach them, testing broadly rather than selling narrow panels and upselling later, and continuing to make the reports genuinely useful rather than simply impressive.
It also means being honest when things go wrong, because occasionally they will. TrueVitals is a small company doing something that matters to people, and it would rather be the business that explains plainly what happened than the one that manages the complaint.
Questions, or something that has not gone the way it should, can be sent to support@truevitals.co.uk.
Up to 230 biomarkers, professional venous collection at 103 UK clinics or at home, and a report that explains what the results actually mean.