A single blood test tells you where you are today. Annual testing tells you where you're heading. Ferritin declining year on year. HbA1c creeping upward. Thyroid antibodies appearing. These trends catch disease in motion — years before a single test would flag anything abnormal. The NHS offers a cardiovascular check once every 5 years from age 40. A comprehensive private blood test annually, from any age, covers every major health system. TrueVitals tests up to 114 biomarkers with AI-powered longitudinal tracking from your second test onwards. £349 per year.
Every one of these is "normal" on each individual test. Only the trajectory reveals the problem.
34 → 37 → 39 → 41 mmol/mol over four years. Each result is below the prediabetes threshold of 42. But the trajectory is unmistakable: this person is heading toward type 2 diabetes. A single test at any point says "normal." The trend says "intervene now." Prediabetes guide.
85 → 62 → 45 → 28 ng/mL over three years. Still above the NHS deficiency threshold of 15 on every test. But iron stores are depleting. By the time ferritin hits 15, the person has been functionally iron deficient for two years. Fatigue guide.
0.85 → 0.95 → 1.08 → 1.22 g/L over four years. Atherogenic particle count rising steadily. Each test might look acceptable in isolation. The trend reveals accelerating cardiovascular risk that warrants lipid-lowering intervention. Heart health guide.
1.8 → 2.4 → 3.1 → 3.9 mIU/L over three years. All within the NHS reference range of 0.4 to 4.5. But TSH is doubling. Thyroid antibodies measured at the same time would reveal whether autoimmune thyroiditis is driving it. A single test at 3.9 just says "normal." Thyroid guide.
22 → 28 → 34 → 39 U/L over four years. Every result below the NHS threshold of 41. But ALT is nearly doubling. Combined with rising fasting insulin and triglycerides, this pattern strongly suggests developing fatty liver disease. Liver guide.
The NHS Health Check is a public health intervention designed to catch population-level cardiovascular risk. It does this well at the cost it is delivered (free). It is not, and was never designed to be, a comprehensive health screen.
NHS Health Check: offered once every 5 years to adults aged 40 to 74 in England. Tests total cholesterol, HDL, fasting glucose or HbA1c, blood pressure, BMI. Calculates a QRISK cardiovascular score. Does not test thyroid, hormones, iron, B12, vitamin D, liver function (beyond lipids), kidney function, ApoB, Lp(a), tumour markers, immunoglobulins, or inflammatory markers.
Comprehensive annual test: available at any age, as frequently as desired. Tests 74 to 200+ biomarkers across every major health system: cardiovascular, metabolic, thyroid, hormonal, liver, kidney, immune, haematological, nutritional, and inflammatory. Provides longitudinal tracking from second test onwards. Identifies trends, not just current values.
They serve different purposes. The NHS check is a population-level cardiovascular screen. A comprehensive annual test is a personal health audit. If you're under 40, the NHS offers nothing. If you're over 40, the NHS offers a narrow check every 5 years. Annual comprehensive testing fills the gap at both ends. NHS vs private guide.
The TrueVitals Ultimate panel covers 114 biomarkers across every major health system. From your second test, the AI tracks every marker over time — directional arrows, percentage changes, trend analysis, and commentary on what improved, declined, or needs attention. £349 per year.
Athletes in heavy training blocks, women in perimenopause or on HRT, men on TRT, anyone managing thyroid disease, and people who've recently made significant dietary or lifestyle changes. Runners guide. TRT guide.
Active management of insulin resistance, iron deficiency, or vitamin D repletion. Post-intervention retesting to confirm corrections are working. Initial TRT monitoring (3, 6, and 12 months).
Everyone else. If you train, eat well, feel fine, and have no known conditions — annual comprehensive testing is the baseline. It establishes your personal norms and catches slow-developing issues before they become clinical.
October or November is ideal in the UK. Vitamin D is at its annual low (before winter supplementation kicks in), giving you the truest baseline. Marathon and endurance season has ended. It's early enough to address any findings before the new year.
Your first TrueVitals report is a comprehensive baseline: 114 biomarkers with AI cross-system analysis and medical professional review. Valuable on its own. But the real power starts with your second test.
From test two onwards, the AI compares every marker against your previous results. Directional arrows show what moved. Percentage changes quantify how much. Trend commentary explains what the shifts likely mean. Markers that were optimal last year but are now borderline get flagged before they become abnormal. The progress dashboard visualises your health trajectory across every system.
This is the difference between reactive healthcare (waiting until something goes wrong) and proactive health intelligence (watching everything in motion and intervening early). The NHS checks your cardiovascular risk once every 5 years. TrueVitals tracks your entire body every year and shows you the direction of travel.
114 biomarkers. AI-powered longitudinal tracking from test two. The most comprehensive annual health check available under £1,000. Less than £1 per day.
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